Sorry, this video is not available in your region
Isco ran the show for Los Blancos in Galicia and got on the scoresheet along with James Rodriguez, who hit a brace, Alvaro Morata, Lucas Vazquez and substitute Casemiro.
With Sergio Ramos suspended and Gareth Bale injured, Zinedine Zidane made nine changes for the trip to the Riazor but Madrid’s reserves made light work of Depor, for whom Florin Andone and Joselu scored consolation goals. Madrid have 78 points from 33 games, while Barcelona have the same tally, having played 34.
Barcelona blitzed Osasuna with four goals in 10 second-half minutes to temporarily move three points clear at the top of La Liga with a 7-1 victory at the Nou Camp.
Luis Enrique rested several of his regular starters, including Luis Suarez, Andres Iniesta and Jordi Alba – an understandable move following gruelling matches against Juventus and Real Madrid, and before the weekend’s derby at Espanyol.
Real Madrid’s Henrico Casemiro No. 14, right, is congratulated by teammates.
It seemed it would not matter much after Lionel Messi struck early and Andre Gomes extended the lead before halftime.
Gomes and Messi both got their second goals of the evening either side of the hour mark to put the game to bed and Paco Alcacer and Javier Mascherano, the latter from the penalty spot, quickly added gloss to the scoreline with just 67 minutes on the clock.
FC Barcelona’s Lionel Messi, second right, kicks to score.
Alcacer became the third player to net a double with four minutes remaining. It was an emphatic scoreline to further increase confidence on the back of Sunday’s El Clasico win over Real at the Bernabeu.
Brazilian striker Luciano Neves scored two goals early in the second half and Leganes comfortably defeated Las Palmas 3-0 to go six points clear of the relegation zone.
The promoted club had lost four in a row and hadn’t won in seven matches. Real Sociedad moved into position to qualify for the Europa League with 3-2 away victory over Valencia.
Originally published as Watch: Messi’s ridiculous brace, but Real keep pace